Repetitive DNA Reeling by the Cascade-Cas3 Complex in Nucleotide Unwinding Steps.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.03.031
Abstract: CRISPR-Cas provides RNA-guided adaptive immunity against invading genetic elements. Interference in type I systems relies on the RNA-guided Cascade complex for target DNA recognition and the Cas3 helicase/nuclease protein for target degradation. Even though the… read more here.
Keywords: dna; repetitive dna; dna reeling; target ... See more keywords