A Facile and Sensitive DNA Sensing of Harmful Algal Blooms Based on Graphene Oxide Nanosheets
Sign Up to like & getrecommendations! Published in 2020 at "Marine Biotechnology"
DOI: 10.1007/s10126-020-09971-6
Abstract: Gene detection has important applications in biology, biomedical engineering, clinical, environmental, and marine fields. Rapid, sensitive, and selective recognition of specific genes is essential in practical applications. In this study, we describe a facile and… read more here.
Keywords: sensitive dna; graphene oxide; oxide nanosheets; dna ... See more keywords
PNA-functionalized magnetic microbeads as substrates for enzyme-labelled voltammetric genoassay for DNA sensing applied to identification of GMO in food.
Sign Up to like & getrecommendations! Published in 2021 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2021.338297
Abstract: A novel enzyme-labelled voltammetric magnetogenoassay for DNA sensing based on the use of carboxyl-surface coated magnetic microbeads functionalized with PNA probes and subsequent read-out on screen-printed electrode (SPE) substrates was developed. The assay was validated… read more here.
Keywords: dna; pna; labelled voltammetric; magnetic microbeads ... See more keywords
Examining Dynamic Emergent Properties of the DNA Sensing Pathway
Sign Up to like & getrecommendations! Published in 2018 at "IFAC-PapersOnLine"
DOI: 10.1016/j.ifacol.2018.09.017
Abstract: Abstract The DNA sensing pathway is a component of the innate immune system that recognizes DNA in the cytosol of cells. Its main purpose after DNA detection is to promote interferon production, which acts as… read more here.
Keywords: examining dynamic; dna sensing; sensing pathway; dynamic emergent ... See more keywords
High Spatial Resolution of Ultrathin Covalent Organic Framework Nanopores for Single-Molecule DNA Sensing.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01708
Abstract: Ultrathin nanosheets of two-dimensional covalent organic frameworks covered a quartz nanopipette and then acted as a nanopore device for single-molecule DNA sensing. Our results showed that a single DNA homopolymer as short as 6 bases… read more here.
Keywords: single molecule; dna; dna sensing; covalent organic ... See more keywords
Erratum: DNA sensing in senescence
Sign Up to like & getrecommendations! Published in 2017 at "Nature Cell Biology"
DOI: 10.1038/ncb3644
Abstract: This corrects the article DOI: 10.1038/ncb3603 read more here.
Keywords: erratum dna; sensing senescence; dna sensing; biology ... See more keywords
TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-02936-3
Abstract: Intracellular nucleic acid sensors often undergo sophisticated modifications that are critical for the regulation of antimicrobial responses. Upon recognition of DNA, the cytosolic sensor cyclic GMP-AMP (cGAMP) synthase (cGAS) produces the second messenger cGAMP, which… read more here.
Keywords: cgas; production; dna; cytosolic dna ... See more keywords
Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abb4565
Abstract: DNA sensing inhibition by viral cGAMP nuclease impairs anti-viral responses and protective immunity. Cells contain numerous immune sensors to detect virus infection. The cyclic GMP-AMP (cGAMP) synthase (cGAS) recognizes cytosolic DNA and activates innate immune… read more here.
Keywords: infection; cgamp nuclease; dna sensing; dna ... See more keywords
cGAS in action: Expanding roles in immunity and inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aat8657
Abstract: cGAS sensing of DNA: A comprehensive look The immune system uses the cGAS-STING (cyclic GMP-AMP synthase–stimulator of interferon genes) signaling pathway to detect the presence of intracellular DNA. This is beneficial because cytosolic DNA is… read more here.
Keywords: innate; cgas; dna; self dna ... See more keywords
Inhibition of DNA-Sensing Pathway by Marek's Disease Virus VP23 Protein through Suppression of Interferon Regulatory Factor 7 Activation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.01934-18
Abstract: Despite widespread vaccination, Marek’s disease (MD) continues to pose major challenges for the poultry industry worldwide. MDV causes immunosuppression and deadly lymphomas in chickens, suggesting that this virus has developed a successful immune evasion strategy.… read more here.
Keywords: vp23; response; dna; activation ... See more keywords
Duck Enteritis Virus Protein Kinase US3 Inhibits DNA Sensing Signaling by Phosphorylating Interferon Regulatory Factor 7
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02299-22
Abstract: Duck enteritis virus (DEV) is a duck alphaherpesvirus that causes an acute and contagious disease with high mortality, resulting in substantial economic losses in the commercial waterfowl industry. The evasion of DNA-sensing pathway-mediated antiviral innate… read more here.
Keywords: dna sensing; duck enteritis; dna; enteritis virus ... See more keywords
Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10121591
Abstract: Nuclear DNA sensors are critical components of the mammalian innate immune system, recognizing the presence of pathogens and initiating immune signaling. These proteins act in the nuclei of infected cells by binding to foreign DNA,… read more here.
Keywords: dna sensors; dna; host antiviral; nuclear dna ... See more keywords