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   Articles with "dna sensor" as a keyword



DNA Sensor ABCF1 Phase Separates With cccDNA to Inhibit Hepatitis B Virus Replication

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202409485

Abstract: Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) contributes to viral persistence and recurrence, however, how the host innate immune system responds to cccDNA is still less known. Here, based on cccDNA‐hepatic proteins interaction… read more here.

Keywords: replication; dna sensor; hepatitis virus; cccdna inhibit ... See more keywords

Immobilization-Free Electrochemical DNA Sensor based on signal cascade amplification strategy.

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recommendations! Published in 2021 at "Biotechnology and applied biochemistry"

DOI: 10.1002/bab.2174

Abstract: The development of convenient and efficient strategies without using complex nanomaterials or enzymes for signal amplification is very important for bioanalytical applications. Herein, a novel electrochemical DNA sensor was developed by harnessing the signal amplification… read more here.

Keywords: target dna; dna; electrochemical dna; dna sensor ... See more keywords

Cytosolic DNA sensor activation inhibits HIV infection of macrophages

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recommendations! Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28253

Abstract: Cytosolic recognition of microbial DNA in macrophages results in the activation of the interferon (IFN)‐dependent antiviral innate immunity. Here, we examined whether activating DNA sensors in peripheral blood monocyte‐derived macrophages (MDMs) can inhibit human immunodeficiency… read more here.

Keywords: dna; dna sensors; hiv infection; dna sensor ... See more keywords

An Ultrasensitive FRET-based DNA Sensor via the Accumulated QD System Derivatized in the Nano-beads

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recommendations! Published in 2018 at "BioChip Journal"

DOI: 10.1007/s13206-018-2406-x

Abstract: Förster resonance energy transfer (FRET) is extremely sensitive to the separation distance between the donor and the acceptor which is ideal for probing such biological phenomena. Also, FRET-based probes have been developing for detecting an… read more here.

Keywords: accumulated system; system; dna; dna sensor ... See more keywords

A label-free electrochemical DNA sensor to identify breast cancer susceptibility

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recommendations! Published in 2017 at "Microchemical Journal"

DOI: 10.1016/j.microc.2017.03.011

Abstract: Abstract Detection of mutations related to cancer predisposition has been an important action in the prevention of cancer and in the cancer genetic profiling. Breast cancer (BRCA) genes mutations are widely known for their relation… read more here.

Keywords: cancer; dna sensor; breast cancer; dna ... See more keywords

The strategies of DNA immobilization and hybridization detection mechanism in the construction of electrochemical DNA sensor: A review

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recommendations! Published in 2017 at "Sensing and bio-sensing research"

DOI: 10.1016/j.sbsr.2017.09.001

Abstract: Abstract In recent years, electrochemical deoxyribonucleic acid (DNA) sensor has recently emerged as promising alternative clinical diagnostic devices especially for infectious disease by exploiting DNA recognition events and converting them into an electrochemical signal. This… read more here.

Keywords: detection; immobilization; dna; electrochemical dna ... See more keywords

Direct E-DNA sensor of Mycobacterium tuberculosis mutant strain based on new nanocomposite transducer (Fc-ac-OMPA/MWCNTs).

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recommendations! Published in 2018 at "Talanta"

DOI: 10.1016/j.talanta.2018.03.025

Abstract: Direct DNA sensor based on new nanocomposite materials (Fc-ac-OMPA/MWCNTs) has been investigated. This nanocomposite was formed by combining the redox oligomer "oligo-methoxy-phenyl-acetonitrile" (Fc-ac-OMPA) and the MWCNTs via a simple π-π stacking interaction in the aim… read more here.

Keywords: based new; ompa mwcnts; dna; dna sensor ... See more keywords
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Molecular diagnostic of toxigenic Corynebacterium diphtheriae strain by DNA sensor potentially suitable for electrochemical point-of-care diagnostic.

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recommendations! Published in 2021 at "Talanta"

DOI: 10.1016/j.talanta.2021.122161

Abstract: The presented study is focused on the development of electrochemical genosensor for detection of tox gene fragment of toxigenic Corynebacterium diphtheriae strain. Together with our previous studies it fulfils the whole procedure for fast and… read more here.

Keywords: diphtheriae strain; toxigenic corynebacterium; corynebacterium diphtheriae; dna sensor ... See more keywords

Sequential Activation of DNA Sensor Enables Correlated Imaging of Dual-Enzyme Activities in Living Cells.

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recommendations! Published in 2025 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.4c05454

Abstract: The DNA repair system relies on the coordinated action of multiple enzymes to maintain genomic stability, with apurinic/apyrimidinic endonuclease 1 (APE1) and flap endonuclease 1 (FEN1) playing pivotal roles in the long-patch base excision repair… read more here.

Keywords: correlated imaging; dna sensor; ape1 fen1; living cells ... See more keywords
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Multichannel DNA sensor-array fingerprints cell states and identifies pharmacological effectors of catabolic processes.

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recommendations! Published in 2019 at "ACS sensors"

DOI: 10.1021/acssensors.9b01009

Abstract: Cells at disease onset are often associated with subtle changes in the expression level of a single or few molecular components, making traditionally used biomarker-driven clinical diagnosis a challenging task. We demonstrate here the design… read more here.

Keywords: pharmacological effectors; array; dna sensor; catabolic processes ... See more keywords

Ultrasensitive pathogen detection with a rolling circle amplification-empowered multiplex electrochemical DNA sensor.

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recommendations! Published in 2021 at "Chemical communications"

DOI: 10.1039/d1cc05181d

Abstract: We report a highly sensitive and selective multiplex assay by empowering an electrochemical DNA sensor with isothermal rolling circle amplification. The assay could simultaneously detect and discriminate three common entero-pathogens in a single reaction, with… read more here.

Keywords: electrochemical dna; dna sensor; rolling circle; circle amplification ... See more keywords