Immobilization-Free Electrochemical DNA Sensor based on signal cascade amplification strategy.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2174
Abstract: The development of convenient and efficient strategies without using complex nanomaterials or enzymes for signal amplification is very important for bioanalytical applications. Herein, a novel electrochemical DNA sensor was developed by harnessing the signal amplification… read more here.
Keywords: target dna; dna; electrochemical dna; dna sensor ... See more keywords
Cytosolic DNA sensor activation inhibits HIV infection of macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28253
Abstract: Cytosolic recognition of microbial DNA in macrophages results in the activation of the interferon (IFN)‐dependent antiviral innate immunity. Here, we examined whether activating DNA sensors in peripheral blood monocyte‐derived macrophages (MDMs) can inhibit human immunodeficiency… read more here.
Keywords: dna; dna sensors; hiv infection; dna sensor ... See more keywords
An Ultrasensitive FRET-based DNA Sensor via the Accumulated QD System Derivatized in the Nano-beads
Sign Up to like & getrecommendations! Published in 2018 at "BioChip Journal"
DOI: 10.1007/s13206-018-2406-x
Abstract: Förster resonance energy transfer (FRET) is extremely sensitive to the separation distance between the donor and the acceptor which is ideal for probing such biological phenomena. Also, FRET-based probes have been developing for detecting an… read more here.
Keywords: accumulated system; system; dna; dna sensor ... See more keywords
A label-free electrochemical DNA sensor to identify breast cancer susceptibility
Sign Up to like & getrecommendations! Published in 2017 at "Microchemical Journal"
DOI: 10.1016/j.microc.2017.03.011
Abstract: Abstract Detection of mutations related to cancer predisposition has been an important action in the prevention of cancer and in the cancer genetic profiling. Breast cancer (BRCA) genes mutations are widely known for their relation… read more here.
Keywords: cancer; dna sensor; breast cancer; dna ... See more keywords
The strategies of DNA immobilization and hybridization detection mechanism in the construction of electrochemical DNA sensor: A review
Sign Up to like & getrecommendations! Published in 2017 at "Sensing and bio-sensing research"
DOI: 10.1016/j.sbsr.2017.09.001
Abstract: Abstract In recent years, electrochemical deoxyribonucleic acid (DNA) sensor has recently emerged as promising alternative clinical diagnostic devices especially for infectious disease by exploiting DNA recognition events and converting them into an electrochemical signal. This… read more here.
Keywords: detection; immobilization; dna; electrochemical dna ... See more keywords
Direct E-DNA sensor of Mycobacterium tuberculosis mutant strain based on new nanocomposite transducer (Fc-ac-OMPA/MWCNTs).
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.03.025
Abstract: Direct DNA sensor based on new nanocomposite materials (Fc-ac-OMPA/MWCNTs) has been investigated. This nanocomposite was formed by combining the redox oligomer "oligo-methoxy-phenyl-acetonitrile" (Fc-ac-OMPA) and the MWCNTs via a simple π-π stacking interaction in the aim… read more here.
Keywords: based new; ompa mwcnts; dna; dna sensor ... See more keywords
Molecular diagnostic of toxigenic Corynebacterium diphtheriae strain by DNA sensor potentially suitable for electrochemical point-of-care diagnostic.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122161
Abstract: The presented study is focused on the development of electrochemical genosensor for detection of tox gene fragment of toxigenic Corynebacterium diphtheriae strain. Together with our previous studies it fulfils the whole procedure for fast and… read more here.
Keywords: diphtheriae strain; toxigenic corynebacterium; corynebacterium diphtheriae; dna sensor ... See more keywords
Multichannel DNA sensor-array fingerprints cell states and identifies pharmacological effectors of catabolic processes.
Sign Up to like & getrecommendations! Published in 2019 at "ACS sensors"
DOI: 10.1021/acssensors.9b01009
Abstract: Cells at disease onset are often associated with subtle changes in the expression level of a single or few molecular components, making traditionally used biomarker-driven clinical diagnosis a challenging task. We demonstrate here the design… read more here.
Keywords: pharmacological effectors; array; dna sensor; catabolic processes ... See more keywords
Ultrasensitive pathogen detection with a rolling circle amplification-empowered multiplex electrochemical DNA sensor.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05181d
Abstract: We report a highly sensitive and selective multiplex assay by empowering an electrochemical DNA sensor with isothermal rolling circle amplification. The assay could simultaneously detect and discriminate three common entero-pathogens in a single reaction, with… read more here.
Keywords: electrochemical dna; dna sensor; rolling circle; circle amplification ... See more keywords
Nanoscale probing and imaging of HIV-1 RNA in cells with a chimeric LNA-DNA sensor.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr08418f
Abstract: Real-time detection and nanoscale imaging of human immunodeficiency virus type 1 ribonucleic acid (HIV-1 RNA) in latently infected cells that persist in people living with HIV-1 on antiretroviral therapy in blood and tissue may reveal… read more here.
Keywords: hiv rna; dna sensor; hiv; lna dna ... See more keywords
Electrosynthesis of electrochemically reduced graphene oxide/polyaniline nanowire/silver nanoflower nanocomposite for development of a highly sensitive electrochemical DNA sensor
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra01301g
Abstract: A novel nanostructured material based on ERGO/PANi NWs/AgNFs was electrosynthesized on a Pt microelectrode and was used for the first time to develop an electrochemical DNA sensor. read more here.
Keywords: electrochemically reduced; dna sensor; electrochemical dna; electrosynthesis electrochemically ... See more keywords