Generating DNA sequence data with limited resources for molecular biology: Lessons from a barcoding project in Indonesia
Sign Up to like & getrecommendations! Published in 2018 at "Applications in Plant Sciences"
DOI: 10.1002/aps3.1167
Abstract: The advent of the DNA sequencing age has led to a revolution in biology. The rapid and cost‐effective generation of high‐quality sequence data has transformed many fields, including those focused on discovering species and surveying… read more here.
Keywords: dna sequence; sequence data; biology; barcoding project ... See more keywords
Epigenetic plasticity in tumor biology
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200092
Abstract: Genetics is the analysis of the heritable variations in DNA sequence that direct the normal development of organisms. Studies probing the humangenomehaveshapedunderstandingofhowourspeciesevolves and adapts to environmental influences, and how disease arises when these processes go… read more here.
Keywords: dna; epigenetic plasticity; dna sequence; plasticity tumor ... See more keywords
A fluorescence method for homogeneous detection of influenza A DNA sequence based on guanine‐quadruplex‐N‐methylmesoporphyrin IX complex and assistance‐DNA inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25422
Abstract: In his study, we report a fluorescence method for homogeneous detection of influenza A (H1N1) DNA sequence based on G‐quadruplex‐NMM complex and assistance‐DNA (A‐DNA) inhibition. The quadruplex‐based functional DNA (QBF‐DNA), composed of a complementary probe… read more here.
Keywords: target h1n1; dna sequence; h1n1 dna; dna ... See more keywords
High-Throughput DNA Sequence-Based Analysis of AMF Communities.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0603-2_9
Abstract: Arbuscular mycorrhizal fungi (AMF) are obligate symbionts of most land plants. They have great ecological and economic impacts as they support plant nutrition and water supply, soil structure, and plant resistance to pathogens. Investigating AMF… read more here.
Keywords: dna sequence; amf communities; throughput dna; high throughput ... See more keywords
Application of Parallel Vector Space Model for Large-Scale DNA Sequence Analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Grid Computing"
DOI: 10.1007/s10723-018-9451-5
Abstract: With rapid advancement in the field of bioinformatics and computational biology, the collected DNA dataset is growing exponentially, doubling after every 18 months. Due to large-scale and complex structure of the DNA dataset, the analysis… read more here.
Keywords: large scale; dna; analysis; scale dna ... See more keywords
DNA sequence-specific dimeric bisbenzimidazoles DBP(n) and DBPA(n) as inhibitors of H-NS silencing in bacterial cells.
Sign Up to like & getrecommendations! Published in 2018 at "Microbiological research"
DOI: 10.1016/j.micres.2017.11.007
Abstract: DNA sequence-specific fluorescent dimeric bisbenzimidazoles DBP(n) and DBPA(n), noncovalently interacting with A-T pairs in the minor groove of double-stranded DNA were used for studying and monitoring the expression of histone-like H-NS-dependent promoters. Histone-like H-NS selectively… read more here.
Keywords: sequence specific; bisbenzimidazoles dbp; dbp dbpa; dimeric bisbenzimidazoles ... See more keywords
iRSpot-DTS: Predict recombination spots by incorporating the dinucleotide-based spare-cross covariance information into Chou's pseudo components.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.11.031
Abstract: Meiotic recombination plays an important role in the process of genetic evolution. Previous researches have shown that the recombination rates provide important information about the mechanism of recombination study. However, at present, most methods ignore… read more here.
Keywords: information; dinucleotide based; recombination; irspot dts ... See more keywords
Fluorescent Polymerase Chain Reaction Nanokit for the Detection of DNA Sequence in Single Living Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02470
Abstract: Here, a fluorescent polymerase chain reaction (PCR) nanokit is established to detect the specific DNA sequence in a single living cell. Different from well-developed protocols to load cell-permeable probes into single cell for recognition, the… read more here.
Keywords: single living; detection; dna; dna sequence ... See more keywords
DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B1-Induced Formamidopyrimidine Guanine Adduct.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.0c00517
Abstract: Dietary exposure to aflatoxins is a significant risk factor in the development of hepatocellular carcinomas. Following bioactivation by microsomal P450s, the reaction of aflatoxin B1 (AFB1) with guanine (Gua) in DNA leads to the formation… read more here.
Keywords: dna; adduct; afb1 fapygua; excision ... See more keywords
HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00978-7
Abstract: The vitamin D receptor/retinoid X receptor-α heterodimer (VDRRXRα) regulates bone mineralization via transcriptional control of osteocalcin (BGLAP) gene and is the receptor for 1α,25-dihydroxyvitamin D3 (1,25D3). However, supra-physiological levels of 1,25D3 activates the calcium-regulating gene… read more here.
Keywords: conformational dynamics; vdr; activator; receptor ... See more keywords
Predicting 3D genome folding from DNA sequence with Akita
Sign Up to like & getrecommendations! Published in 2020 at "Nature methods"
DOI: 10.1038/s41592-020-0958-x
Abstract: In interphase, the human genome sequence folds in three dimensions into a rich variety of locus-specific contact patterns. Cohesin and CTCF are key regulators; perturbing the levels of either greatly disrupts genome-wide folding as assayed… read more here.
Keywords: genome folding; predicting genome; folding dna; dna sequence ... See more keywords