Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12206
Abstract: Abstract It has been demonstrated recently that extracellular vesicles (EVs) carry DNA; however, many fundamental features of DNA in EVs (EV‐DNA) remain elusive. In this study, a laboratory‐built nano‐flow cytometer (nFCM) that can detect single… read more here.
Keywords: dna evs; dna; dna single; vesicle ... See more keywords
Imaging DNA single-strand breaks generated by reactive oxygen species using a liquid crystal-based sensor.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2018.06.009
Abstract: DNA single-strand breaks (SSBs) have attracted much interest since they are highly related to carcinogenesis and ageing. Herein, we report a new liquid crystal (LC)-based sensor for the detection of DNA SSBs generated by reactive… read more here.
Keywords: dna; dna single; liquid crystal; strand breaks ... See more keywords
Detecting topological variations of DNA at single-molecule level
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-07924-1
Abstract: In addition to their use in DNA sequencing, ultrathin nanopore membranes have potential applications in detecting topological variations in deoxyribonucleic acid (DNA). This is due to the fact that when topologically edited DNA molecules, driven… read more here.
Keywords: single molecule; dna; dna single; detecting topological ... See more keywords