The Random Oligonucleotide-Primed Synthesis Assay for the Quantification of DNA Strand Breaks.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4899-7708-3_18
Abstract: DNA strand breaks arise from normal cellular processes such as replication, transcription, and DNA repair as well as spontaneous DNA damage caused by cell metabolic activities. In addition, strand breaks occur due to direct or… read more here.
Keywords: random oligonucleotide; dna; strand breaks; dna strand ... See more keywords
Introduction to the multi-author-review: emerging advances in the structural chemistry of DNA strand break repair
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03364-2
Abstract: DNA strand breaks present a complex challenge for our cells, and the integrity of the DNA damage response machinery is critical for preventing cancer, premature aging, and neurodegenerative syndromes amongst other ailments. This multi-author review… read more here.
Keywords: chemistry; multi author; author review; strand break ... See more keywords
DNA coding and Gödel numbering
Sign Up to like & getrecommendations! Published in 2022 at "Physica A: Statistical Mechanics and its Applications"
DOI: 10.1016/j.physa.2022.127053
Abstract: Evolution consists of distinct stages: cosmological, biological, linguistic. Since biology verges on natural sciences and linguistics, we expect that it shares structures and features from both forms of knowledge. Indeed, in DNA we encounter the… read more here.
Keywords: dna; coding del; godel; dna strand ... See more keywords
Cooperative Branch Migration: A Mechanism for Flexible Control of DNA Strand Displacement.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c10797
Abstract: DNA strand displacement plays an essential role in the field of dynamic DNA nanotechnology. However, flexible regulation of strand displacement remains a significant challenge. Most previous regulatory tools focused on controllable activation of toehold and… read more here.
Keywords: strand displacement; dna; branch migration; dna strand ... See more keywords
Four-Analog Computation Based on DNA Strand Displacement
Sign Up to like & getrecommendations! Published in 2017 at "ACS Omega"
DOI: 10.1021/acsomega.7b00572
Abstract: DNA strand displacement plays an important role in biological computations. The inherent advantages of parallelism, high storability, and cascading have resulted in increased functional circuit realization of DNA strand displacement on the nanoscale. Herein, we… read more here.
Keywords: analog computation; strand displacement; dna strand; computation ... See more keywords
Design of a Single-Channel Chaotic Secure Communication System Implemented by DNA Strand Displacement.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00509
Abstract: DNA strand displacement (DSD) is regarded as a foundation for the construction of biological computing systems because of the predictability of DNA molecular behaviors. Some complex system dynamics can be approximated by cascading DSD reaction… read more here.
Keywords: system; dna strand; chaotic secure; communication ... See more keywords
Massively Parallel DNA Computing Based on Domino DNA Strand Displacement Logic Gates.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00270
Abstract: DNA computing has gained considerable attention due to the characteristics of high-density information storage and high parallel computing for solving computational problems. Building addressable logic gates with biomolecules is the basis for establishing biological computers.… read more here.
Keywords: logic gates; dna strand; dna; domino ... See more keywords
Orthogonal Enzyme-Driven Timers for DNA Strand Displacement Reactions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06599
Abstract: Here, we demonstrate a strategy to rationally program a delayed onset of toehold-mediated DNA strand displacement reactions (SDRs). The approach is based on blocker strands that efficiently inhibit the strand displacement by binding to the… read more here.
Keywords: dna; dna strand; displacement reactions; strand displacement ... See more keywords
DNA Strand Buffers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b05373
Abstract: A buffer reaction actively resists changes to the concentration of a chemical species. Typically, buffering reactions have only been able to regulate the concentration of hydronium (i.e., pH) and other ions. Here, we develop a… read more here.
Keywords: concentration; strand buffers; dna strand;
Dynamic protein assembly by programmable DNA strand displacement
Sign Up to like & getrecommendations! Published in 2018 at "Nature Chemistry"
DOI: 10.1038/s41557-018-0016-9
Abstract: AbstractInspired by the remarkable ability of natural protein switches to sense and respond to a wide range of environmental queues, here we report a strategy to engineer synthetic protein switches by using DNA strand displacement… read more here.
Keywords: protein; strand displacement; dna strand;
Boolean logic gate based on DNA strand displacement for biosensing: current and emerging strategies.
Sign Up to like & getrecommendations! Published in 2021 at "Nanoscale horizons"
DOI: 10.1039/d0nh00587h
Abstract: DNA computers are considered one of the most prominent next-generation molecular computers that perform Boolean logic using DNA elements. DNA-based Boolean logic gates, especially DNA strand displacement-based logic gates (SDLGs), have shown tremendous potential in… read more here.
Keywords: strand displacement; dna strand; boolean logic;