DNA structural features of eukaryotic TATA‐containing and TATA‐less promoters
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12166
Abstract: Eukaryotic genes can be broadly classified as TATA‐containing and TATA‐less based on the presence of TATA box in their promoters. Experiments on both classes of genes have revealed a disparity in the regulation of gene… read more here.
Keywords: tata; dna structural; containing tata; tata containing ... See more keywords
Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.102868
Abstract: Background Point mutations and structural variations (SVs) in mitochondrial DNA (mtDNA) contribute to many neurodegenerative diseases. Technical limitations and heteroplasmy, however, have impeded their identification, preventing these changes from being examined in neurons in healthy… read more here.
Keywords: mitochondrial dna; mitosv seq; cell; dna structural ... See more keywords
Delineation of the DNA Structural Features of Eukaryotic Core Promoter Classes
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c04603
Abstract: The eukaryotic transcription is orchestrated from a chunk of the DNA region stated as the core promoter. Multifarious and punctilious core promoter signals, viz., TATA-box, Inr, BREs, and Pause Button, are associated with a subset… read more here.
Keywords: promoter; dna structural; core promoter; promoter classes ... See more keywords
Creation and resolution of non-B-DNA structural impediments during replication
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in biochemistry and molecular biology"
DOI: 10.1080/10409238.2022.2121803
Abstract: Abstract During replication, folding of the DNA template into non-B-form secondary structures provides one of the most abundant impediments to the smooth progression of the replisome. The core replisome collaborates with multiple accessory factors to… read more here.
Keywords: replication; creation resolution; dna structural; resolution non ... See more keywords
Structural predictions of protein–DNA binding: MELD-DNA
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad013
Abstract: Abstract Structural, regulatory and enzymatic proteins interact with DNA to maintain a healthy and functional genome. Yet, our structural understanding of how proteins interact with DNA is limited. We present MELD-DNA, a novel computational approach… read more here.
Keywords: dna; structural predictions; meld dna; protein dna ... See more keywords
Bisulfite probing reveals DNA structural intricacies
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad115
Abstract: Abstract In recent decades, study of DNA structure has largely been focused on the interrelationships between nucleotides at the level of nearest neighbours. A little-utilized approach to probing structure on a larger scale is non-denaturing… read more here.
Keywords: probing reveals; bisulfite probing; structural intricacies; reveals dna ... See more keywords