B-DNA Structure and Stability: The Role of Nucleotide Composition and Order.
Sign Up to like & getrecommendations! Published in 2022 at "ChemistryOpen"
DOI: 10.1002/open.202200013
Abstract: Invited for this month's cover are the groups of Célia Fonseca Guerra at the Vrije Universiteit Amsterdam and Leiden University, Giampaolo Barone from the Università degli Studi di Palermo, and F. Matthias Bickelhaupt at Vrije… read more here.
Keywords: stability role; dna; role nucleotide; dna structure ... See more keywords
Integrating DNA structure switch with branched hairpins for the detection of uracil-DNA glycosylase activity and inhibitor screening.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2017.10.052
Abstract: The detection of uracil-DNA glycosylase (UDG) activity is pivotal for its biochemical studies and the development of drugs for UDG-related diseases. Here, we explored an integrated DNA structure switch for high sensitive detection of UDG… read more here.
Keywords: dna structure; structure switch; detection; dna ... See more keywords
Non-duplex G-Quadruplex DNA Structure: A Developing Story from Predicted Sequences to DNA Structure-Dependent Epigenetics and Beyond.
Sign Up to like & getrecommendations! Published in 2020 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00431
Abstract: ConspectusThe story of the non-duplex DNA form known as the G-quadruplex (G4) has traversed a winding path. From initial skepticism followed by debate to a surge in interest, the G4 story intertwines many threads. Starting… read more here.
Keywords: dna structure; story; non duplex; structure ... See more keywords
DNA Structure-Stabilized Liquid-Liquid Self-Assembled Ordered Au Nanoparticle Interface for Sensitive Detection of MiRNA 155.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02336
Abstract: Au nanoparticles (Au NPs) can be self-assembled in a bottom-up orderly manner at the oil-water interface, which is widely used as SERS platforms, but the stability of the Au NP interface needs to be improved… read more here.
Keywords: dna structure; dna; self assembled; mirna 155 ... See more keywords
Electrochemical Aptamer Biosensor Based on ATP-Induced 2D DNA Structure Switching for Rapid and Ultrasensitive Detection of ATP.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00613
Abstract: Herein, a two-dimensional (2D) DNA structure with multiple ATP aptamers was elegantly designed to establish an electrochemical biosensor for rapid and sensitive detection of ATP based on ATP-induced structure switching. Concretely, the prepared 2D DNA… read more here.
Keywords: atp aptamers; detection; structure; dna structure ... See more keywords
Emulating Titin by a Multidomain DNA Structure.
Sign Up to like & getrecommendations! Published in 2022 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.2c00585
Abstract: Titin, a giant protein containing multiple tandem domains, is essential in maintaining the superior mechanical performance of muscle. The consecutive and reversible unfolding and refolding of the domains are crucial for titin to serve as… read more here.
Keywords: multidomain dna; dna; titin; titin multidomain ... See more keywords
Evaluation of sperm DNA structure, fragmentation and decondensation: an essential tool in the assessment of male infertility
Sign Up to like & getrecommendations! Published in 2017 at "Translational Andrology and Urology"
DOI: 10.21037/tau.2017.03.11
Abstract: The intrinsic primordial role of the oocyte in contributing to successful embryogenesis must first be considered and acknowledged. Capacity for DNA repair in the oocyte is important, but is finite and decreases with age. Multiple… read more here.
Keywords: dna structure; decondensation; dna; sperm dna ... See more keywords
Transformation characteristics of A-DNA in salt solution revealed through molecular dynamics simulations.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical chemistry"
DOI: 10.2139/ssrn.4078736
Abstract: The structure of A-DNA with biological activity is double helix. Researches of A-DNA structure have wide application on the development of DNA drug. In aqueous solution, the structure of A-DNA will have a free transformation… read more here.
Keywords: structure; molecular dynamics; salt solution; dna structure ... See more keywords