Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2018 at "MedChemComm"
DOI: 10.1039/c8md00301g
Abstract: A series of novel unique structural organophosphorus aminopyrimidines were developed as potential DNA-targeting membrane active inhibitors through an efficient one-pot procedure from aldehydes, phosphonate and aminopyrimidine. The biological assay revealed that some of the prepared… read more here.
Keywords: unique structural; dna targeting; dna; targeting membrane ... See more keywords
An amphiphilic BODIPY-based selective probe for parallel G4 DNA targeting via disaggregation-induced emission
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DOI: 10.1039/d0nj02887h
Abstract: The implication of G4 DNA in biologically important roles has prompted a search for methods of selective recognition of and interaction with G4 agents. Because G4 DNA structures can adopt various topologies, attaining a specific… read more here.
Keywords: disaggregation induced; dna targeting; parallel dna; dna ... See more keywords