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Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202000835
Abstract: The chemical and self‐assembly properties of nucleic acids make them ideal for the construction of discrete structures and stimuli‐responsive devices for a diverse array of applications. Amongst the various three‐dimensional assemblies, DNA tetrahedra are of…
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Keywords:
dna tetrahedra;
therapeutic delivery;
recent advances;
advances dna ... See more keywords
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Published in 2021 at "Small"
DOI: 10.1002/smll.202007355
Abstract: The reversible and switchable triggered reconfiguration of tetrahedra nanostructures from monomer tetrahedra structures into dimer or trimer structures is introduced. The triggered bridging of monomer tetrahedra by K+ -ion-stabilized G-quadruplexes or T-A•T triplexes leads to…
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Keywords:
multiplexed mirna;
trimerization dna;
triggered dimerization;
dimerization trimerization ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202204108
Abstract: The assembly of adenosine triphosphate (ATP)-responsive and miRNA-responsive DNA tetrahedra-functionalized carboxymethyl cellulose hydrogel microcapsules is presented. The microcapsules are loaded with the doxorubicin-dextran drug or with CdSe/ZnS quantum dots as a drug model. Selective unlocking…
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Keywords:
drug;
hydrogel microcapsules;
responsive drug;
dna tetrahedra ... See more keywords
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Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc01123b
Abstract: The potential for using DNA nanostructures for drug delivery applications requires understanding and ideally tuning their biostability. Here we investigate how biological degradation varies with size of a DNA nanostructure. We designed DNA tetrahedra of…
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Keywords:
biostability;
dna tetrahedra;
size biostability;
role size ... See more keywords