Biomimetic Nanoerythrosome‐Coated Aptamer–DNA Tetrahedron/Maytansine Conjugates: pH‐Responsive and Targeted Cytotoxicity for HER2‐Positive Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109609
Abstract: DNA materials have emerged as potential nanocarriers for targeted cancer therapy to precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of DNA materials due to their interception by the reticuloendothelial system… read more here.
Keywords: dna; her2 positive; drug; cancer ... See more keywords
DNA Tetrahedron Framework Guided Conjugation and Assembly of Gold Nanoparticles.
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DOI: 10.1002/cplu.202200159
Abstract: Au nanoparticles (AuNPs) have been extensively used to assemble programmable structures that feature various functions. One central challenge of precisely directed assembly is to make valence-programmable building blocks. Herein, we use the DNA tetrahedron framework… read more here.
Keywords: framework guided; guided conjugation; tetrahedron framework; tetrahedron ... See more keywords
Highly sensitive detection of multiple antibiotics based on DNA tetrahedron nanostructure-functionalized magnetic beads.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.04.024
Abstract: Functional DNAs-functionalized magnetic beads (MBs) offer great potential in bioanalysis field because of their target recognition and magnetic separation functions. However, the recognition capability and hybridization affinity of DNA probes often suffer from limited available… read more here.
Keywords: dna tetrahedron; tetrahedron nanostructure; tet; detection ... See more keywords
Ratiometric immunosensor with DNA tetrahedron nanostructure as high-performance carrier of reference signal and its applications in selective phoxim determination for vegetables.
Sign Up to like & getrecommendations! Published in 2022 at "Food chemistry"
DOI: 10.1016/j.foodchem.2022.132445
Abstract: A ratiometric electrochemical immunosensor, based on DNA tetrahedron nanostructure (DTNS), is introduced for vegetable phoxim determination. DTNS spontaneously adheres onto gold-nanoparticle-modified electrode and forms stable three-dimensional structure, providing plenty of binding sites to the built-in… read more here.
Keywords: reference; tetrahedron nanostructure; immunosensor; phoxim determination ... See more keywords
A dual-targeting DNA tetrahedron nanocarrier for breast cancer cell imaging and drug delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2017.11.034
Abstract: To enhance efficacy of chemotherapy and achieve real-time imaging of cancer cells, it is crucial to develop nanocarriers with targeted drug delivery capacity and fluorescence property for cancer theranostics. Herein, a dual-targeting DNA tetrahedron nanocarrier… read more here.
Keywords: cancer; muc1; dna tetrahedron; drug delivery ... See more keywords
DNAzyme-based sensing probe protected by DNA tetrahedron from nuclease degradation for the detection of lead ions.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122543
Abstract: Lead poisoning endangers soil, plants and human health due to its toxic effect. It is urgent to develop ideal tool for the in vivo detection of Pb2+.In this study, tetrahedron-based Pb2+-sensitive DNAzyme sensor (TPS) is… read more here.
Keywords: pb2; sensing probe; detection; dnazyme ... See more keywords
A Nongenetic Proximity-Induced FRET Strategy Based on DNA Tetrahedron for Visualizing the Receptor Dimerization.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c02330
Abstract: Protein dimerization or oligomerization is a key factor in signal transduction process. It is of great significance to develop novel strategies for investigating protein dimerization in cells and in vivo. Herein, we report a nongenetic… read more here.
Keywords: dimerization; strategy; dna tetrahedron; receptor ... See more keywords
Activatable Dual Cancer-Related RNA Imaging and Combined Gene-Chemotherapy through the Target-Induced Intracellular Disassembly of Functionalized DNA Tetrahedron.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00364
Abstract: The desire for a cancer theranostic system with simultaneously accurate diagnosis and efficient therapy is undeniably interminable. Heretofore, theranostic systems with simple components were designed for cancer theranostics but with confined accuracy of diagnosis and… read more here.
Keywords: activatable cancer; dna tetrahedron; cancer; theranostic system ... See more keywords
A DNA Tetrahedron Nanoprobe with Controlled Distance of Dyes for Multiple Detection in Living Cells and in Vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b00889
Abstract: Multicomponent quantitative detection in living samples is becoming increasingly important; however, the current detection strategy may cause fluorescence self-quenching and reduce the sensitivity of detection. To solve the problem, we develop a DNA tetrahedral nanoprobe… read more here.
Keywords: detection; detection living; fluorescence; living cells ... See more keywords
A Multifunctional Double Bundle DNA Tetrahedron for Efficient Regulation of Gene Expression.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c08886
Abstract: DNA nanostructures have garnered considerable interest as research tools in the field of cell biology and pathology. Herein, we develop an addressable double bundle DNA tetrahedron with distinct modification sites to load multiple functional components… read more here.
Keywords: dna; biology; dna tetrahedron; gene ... See more keywords
Simultaneous Imaging of Dual microRNAs in Cancer Cells through Catalytic Hairpin Assembly on a DNA Tetrahedron.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c23227
Abstract: Accurate detection and imaging of tumor-related microRNA (miRNA) in living cells hold great promise for early cancer diagnosis and prognosis. One of the challenges is to develop methods that enable the identification of multiple miRNAs… read more here.
Keywords: tumor; cancer; catalytic hairpin; hairpin assembly ... See more keywords