Control of the stepwise assembly-disassembly of DNA origami nanoclusters by pH stimuli-responsive DNA triplexes.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr05047g
Abstract: We present the pH-triggered reversible assembly of DNA origami clusters in a stepwise fashion. The structure formation and dissociation are controlled by a series of consecutive pH-stimulation processes that rely on the triplex-to-duplex transition of… read more here.
Keywords: control stepwise; dna triplexes; stepwise assembly; dna origami ... See more keywords
Three's a crowd – stabilisation, structure, and applications of DNA triplexes
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc01793h
Abstract: DNA is a strikingly flexible molecule and can form a variety of secondary structures, including the triple helix, which is the subject of this review. The DNA triplex may be formed naturally, during homologous recombination,… read more here.
Keywords: dna; dna triplexes; three crowd; crowd stabilisation ... See more keywords
Atypical structures of GAA/TTC trinucleotide repeats underlying Friedreich’s ataxia: DNA triplexes and RNA/DNA hybrids
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa665
Abstract: Abstract Expansion of the GAA/TTC repeats in the first intron of the FXN gene causes Friedreich’s ataxia. Non-canonical structures are linked to this expansion. DNA triplexes and R-loops are believed to arrest transcription, which results… read more here.
Keywords: friedreich ataxia; dna triplexes; gaa ttc; dna ... See more keywords