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Published in 2017 at "Advanced functional materials"
DOI: 10.1002/adfm.201604139
Abstract: The promise of DNA vaccines is far-reaching. However, the development of potent immunization methods remains a key challenge for its use in clinical applications. Here, an approach for in vivo DNA vaccination by electrically activated…
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Keywords:
plasmonic nanoparticles;
dna vaccination;
hepatitis virus;
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Published in 2018 at "Current opinion in biomedical engineering"
DOI: 10.1016/j.cobme.2018.09.003
Abstract: Non-viral gene delivery via the oral route is a promising strategy for improving outcomes of DNA vaccination and gene therapy applications. Unlike traditional parenteral administration routes, the oral route is a non-invasive approach that lends…
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Keywords:
non viral;
viral gene;
gene delivery;
gene ... See more keywords
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Published in 2018 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2018.09.018
Abstract: Schistosomiasis is a fatal disease that has a negative impact on health and economics. Praziquantel (PZQ) is the drug of choice for schistosomiasis treatment, but it has no prophylactic effect; therefore, vaccination is an essential…
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Keywords:
mansoni;
dna;
infection;
dna vaccinated ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0191927
Abstract: In this study we analysed the effects of prophylactic biolistic DNA vaccination with plasmids encoding the encephalitogenic protein myelin oligodendrocyte glycoprotein (MOG) on the severity of a subsequently MOGp35-55-induced EAE and on the underlying immune…
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Keywords:
mog;
expression;
promoter;
vaccination ... See more keywords
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Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.752444
Abstract: Conventional DNA vaccine strategies usually employ a regimen of immunizations at 2-week or longer intervals to induce effective memory cell-dependent immune responses. Clinical cancer treatment requires a faster immunization strategy to contend with tumor progression.…
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Keywords:
vaccination;
strategy;
fast dna;
cd8 cd11c ... See more keywords
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Published in 2021 at "Vaccines"
DOI: 10.3390/vaccines9020163
Abstract: Traditionally, commercial testing for vaccine efficacy has relied on the mass infection of vaccinated and unvaccinated animals and the comparison of mortality prevalence and incidence. For some infection models where disease does not cause mortality…
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Keywords:
dna;
infection;
vaccine;
dna vaccination ... See more keywords