Abstract LB-119: Targeting DNA-PK via small molecule inhibitors of the Ku-DNA interaction
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DOI: 10.1158/1538-7445.am2017-lb-119
Abstract: DNA-PK, the DNA-dependent protein kinase, is a validated target for cancer therapeutics that drives the DNA damage response and plays a critical role in the nonhomologous end joining (NHEJ) DNA repair pathway. Inhibition of DNA-PK… read more here.
Keywords: targeting dna; dna; dna interaction; cancer ... See more keywords