The effect of Dnaaf5 gene dosage on primary ciliary dyskinesia phenotypes.
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DOI: 10.1172/jci.insight.168836
Abstract: DNAAF5 is a dynein motor assembly factor associated with the autosomal heterogenic recessive condition of motile cilia, primary ciliary dyskinesia (PCD). The effects of allele heterozygosity on motile cilia function are unknown. We used CRISPR-Cas9… read more here.
Keywords: gene dosage; dnaaf5; primary ciliary; ciliary dyskinesia ... See more keywords