Identification of a Ligand-Binding Site on the Staphylococcus aureus DnaG Primase C-Terminal Domain.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.6b01273
Abstract: The interface between the DnaG primase C-terminal domain (CTD) and the N-terminal domain of DnaB helicase is essential for bacterial DNA replication because it allows coordinated priming of DNA synthesis at the replication fork while… read more here.
Keywords: terminal domain; ctd; primase; conformation ... See more keywords
Theoretical Development of DnaG Primase as a Novel Narrow-Spectrum Antibiotic Target
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DOI: 10.1021/acsomega.1c05928
Abstract: The widespread use of antibiotics to treat infections is one of the reasons that global mortality rates have fallen over the past 80 years. However, antibiotic use is also responsible for the concomitant rise in… read more here.
Keywords: theoretical development; primase novel; development dnag; novel narrow ... See more keywords