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Published in 2017 at "Infection and Immunity"
DOI: 10.1128/iai.00651-17
Abstract: ABSTRACT The fusion protein DnaJ-ΔA146Ply could induce cross-protective immunity against pneumococcal infection via mucosal and subcutaneous immunization in mice in the absence of additional adjuvants. DnaJ and Ply are both Toll-like receptor 4 (TLR4) but…
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Keywords:
toll like;
dnaj a146ply;
tlr2;
dnaj ... See more keywords
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Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00686
Abstract: Subunit vaccines that are poorly immunogenic are often combined with adjuvants for immunization. Our previous research identified a pneumolysin variant (ΔA146Ply), a Toll-like receptor 4 agonist, that was an effective adjuvant in the protection of…
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Keywords:
dnaj;
fusion protein;
subcutaneous immunization;
dnaj a146ply ... See more keywords