Articles with "dnaj a146ply" as a keyword



Photo by efekurnaz from unsplash

Expression of Toll-Like Receptor 2 by Dendritic Cells Is Essential for the DnaJ-ΔA146Ply-Mediated Th1 Immune Response against Streptococcus pneumoniae

Sign Up to like & get
recommendations!
Published in 2017 at "Infection and Immunity"

DOI: 10.1128/iai.00651-17

Abstract: ABSTRACT The fusion protein DnaJ-ΔA146Ply could induce cross-protective immunity against pneumococcal infection via mucosal and subcutaneous immunization in mice in the absence of additional adjuvants. DnaJ and Ply are both Toll-like receptor 4 (TLR4) but… read more here.

Keywords: toll like; dnaj a146ply; tlr2; dnaj ... See more keywords
Photo by cdc from unsplash

Subcutaneous Immunization with Fusion Protein DnaJ-ΔA146Ply without Additional Adjuvants Induces both Humoral and Cellular Immunity against Pneumococcal Infection Partially Depending on TLR4

Sign Up to like & get
recommendations!
Published in 2017 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2017.00686

Abstract: Subunit vaccines that are poorly immunogenic are often combined with adjuvants for immunization. Our previous research identified a pneumolysin variant (ΔA146Ply), a Toll-like receptor 4 agonist, that was an effective adjuvant in the protection of… read more here.

Keywords: dnaj; fusion protein; subcutaneous immunization; dnaj a146ply ... See more keywords