Abstract 6803: RNF5-DNAJA1 axis dictates selinexor sensitivity of multiple myeloma by regulating mitochondrial function
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DOI: 10.1158/1538-7445.am2025-6803
Abstract: Selinexor is a First-in-Class XPO1 Inhibitor approved for relapsed or refractory multiple myeloma (RRMM), but the overall response rate remains unsatisfactory. The main mechanism by which Selinexor kill MM cells is to suppress the export… read more here.
Keywords: multiple myeloma; rnf5 dnaja1; dnaja1 axis; regulating mitochondrial ... See more keywords