Safeguarding Lysosomal Homeostasis by DNAJC5/CSPĪ±-Mediated Unconventional Protein Secretion and Endosomal Microautophagy
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DOI: 10.3389/fcell.2022.906453
Abstract: Neuronal ceroid lipofuscinosis (NCL) is a collection of genetically inherited neurological disorders characterized by vision loss, seizure, brain death, and premature lethality. At the cellular level, a key pathologic hallmark of NCL is the build-up… read more here.
Keywords: lysosomal homeostasis; dnajc5 csp; endosomal microautophagy; unconventional protein ... See more keywords