Differential DNA Methylation of Human Metastable Epialleles in Guatemalan Infants at Birth Due to Timing of a Maternal Lipid-Based Nutrition Supplement and Pre-Pregnancy BMI (P11-139-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz048.p11-139-19
Abstract: Objectives Human metastable epialleles (MEs) are specific regions that are systemically methylated (lack tissue specificity), stable over time, and variably expressed between individuals. DNA methylation (DNAme) of MEs have been previously reported to be altered… read more here.
Keywords: ppbmi; dname; timing maternal; human metastable ... See more keywords
Transgenerational impact of grand-paternal lifetime exposures to both folic acid deficiency and supplementation on genome-wide DNA methylation in male germ cells.
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DOI: 10.1111/andr.13399
Abstract: BACKGROUND DNA methylation (DNAme) erasure and reacquisition occurs during prenatal male germ cell development; some further remodelling takes place after birth during spermatogenesis. Environmental insults during germline epigenetic reprogramming may affect DNAme, presenting a potential… read more here.
Keywords: methylation; germ; folic acid; dname ... See more keywords
Abstract 7027: Direct multi-omics for the masses: Linking DNA methylation to chromatin targets via TEM-seq
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DOI: 10.1158/1538-7445.am2024-7027
Abstract: DNA methylation (DNAme) is an epigenetic mark that includes the modification of cytosine resides (5mC) within CpG islands. In addition to well characterized roles regulating gene expression, imprinting and silencing parasitic DNA elements, the misregulation… read more here.
Keywords: tem seq; methylation; chromatin; tem ... See more keywords
Methylation patterns in serum DNA for early identification of disseminated breast cancer
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DOI: 10.1186/s13073-017-0499-9
Abstract: BackgroundMonitoring treatment and early detection of fatal breast cancer (BC) remains a major unmet need. Aberrant circulating DNA methylation (DNAme) patterns are likely to provide a highly specific cancer signal. We hypothesized that cell-free DNAme… read more here.
Keywords: breast; breast cancer; serum; cancer ... See more keywords