A "signal-on" electrochemical biosensor based on DNAzyme-driven bipedal DNA walkers and TdT-mediated cascade signal amplification strategy.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.12.008
Abstract: In this work, a dual amplified signal enhancement approach based on coupling deoxyribozyme (DNAzyme)-driven bipedal DNA walkers (BDW) and terminal deoxynucleotidyl transferase (TdT)-mediated DNA elongation signal amplifications has been developed for highly sensitive and label-free… read more here.
Keywords: tdt mediated; dnazyme driven; bipedal dna; dna ... See more keywords
DNAzyme-Driven Dynamic Cycling Biosensor with Dynamic Fluorescent and Cumulative Electrochemiluminescence Monitoring of Single-Nucleotide Variants.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c04377
Abstract: Nucleic acid-based constitutional dynamic networks (CDNs) can mimic biological events while revealing complex biological processes and their functionalities. In this study, we present a novel dual-signal biosensor that leverages a dissipative DNAzyme-driven network for the… read more here.
Keywords: chemistry; biosensor; driven dynamic; dnazyme driven ... See more keywords