Identification of biomarkers for drug-resistant endometriosis using clinical proteomics
Sign Up to like & getrecommendations! Published in 2021 at "Human Cell"
DOI: 10.1007/s13577-020-00465-0
Abstract: Dienogest (DNG), is an effective and widely used progestin used in the treatment of endometriosis, yet clinically, a subset of cases show resistance to DNG treatment. During a previous investigation on the effect of DNG… read more here.
Keywords: endometriosis; drug resistant; resistant endometriosis; dng ... See more keywords
A multicenter, randomized, placebo-controlled, double-blind, comparative study of dienogest at 1 mg/day in patients with primary and secondary dysmenorrhea.
Sign Up to like & getrecommendations! Published in 2020 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2019.11.010
Abstract: OBJECTIVE To evaluate the efficacy and safety of dienogest (DNG), a progestational 19-norsteroid, in patients with primary and secondary dysmenorrhea. DESIGN Phase III, randomized, double-blind, multicenter, placebo-controlled study. SETTING Clinical study sites in Japan. PATIENT(S)… read more here.
Keywords: secondary dysmenorrhea; study; primary secondary; dng ... See more keywords
Prediction of the final menstrual period in women taking Dienogest using estradiol and follicle-stimulating hormone values: a case-control study.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine journal"
DOI: 10.1507/endocrj.ej22-0158
Abstract: Dienogest (DNG) is widely used to treat dysmenorrhea associated with estrogen-dependent diseases such as endometriosis and adenomyosis. DNG becomes unnecessary after menopause when estrogen secretion declines drastically. However, there are no clear criteria for when… read more here.
Keywords: hormone; dng; control; group ... See more keywords
Dienogest May Reduce Estradiol- and Inflammatory Cytokine-Induced Cell Viability and Proliferation and Inhibit the Pathogenesis of Endometriosis: A Cell Culture- and Mouse Model-Based Study
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112992
Abstract: Dienogest (DNG) is a therapeutic medication used in endometriosis treatment. Limited data are available regarding its mechanism of action on endometrial cells. Using in vivo and in vitro models, we investigated whether DNG treatment causes… read more here.
Keywords: cell; dng; endometriosis; treatment ... See more keywords