Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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DOI: 10.1016/j.cell.2021.05.021
Abstract: Summary Cross-presentation of antigens from dead tumor cells by type 1 conventional dendritic cells (cDC1s) is thought to underlie priming of anti-cancer CD8+ T cells. cDC1 express high levels of DNGR-1 (a.k.a. CLEC9A), a receptor… read more here.
Keywords: presentation; secreted gelsolin; cross presentation; dngr dependent ... See more keywords