Pervasive role of the long noncoding RNA DNM3OS in development and diseases
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1736
Abstract: Thousands of unique noncoding RNAs (ncRNAs) are expressed in human cells, some are tissue or cell type specific whereas others are considered as house‐keeping molecules. Studies over the last decade have modified our perception of… read more here.
Keywords: dnm3os; role; long noncoding; pervasive role ... See more keywords
LncRNA DNM3OS promotes proliferation and inhibits apoptosis through modulating IGF1 expression by sponging MiR-126 in CHON-001 cells
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic Pathology"
DOI: 10.1186/s13000-019-0877-2
Abstract: BackgroundAs a degenerative disease, osteoarthritis (OA) greatly affects aged population. The human chondrocyte cell line CHON-001, derived from normal human articular cartilage, has been widely used in vitro in osteoarthritis models. In order to better… read more here.
Keywords: mir 126; chon 001; proliferation; expression ... See more keywords
miR-214 and its primary transcript Dnm3os regulate fibrosis and inflammation through RAGE signalling in diabetic kidney disease.
Sign Up to like & getrecommendations! Published in 2025 at "Diabetes"
DOI: 10.2337/db24-0121
Abstract: Pathological signaling via the receptor for advanced glycation end-products (RAGE) is critical in diabetic kidney disease (DKD) development, while RAGE deletion is reno-protective. Non-coding RNAs (ncRNAs), including microRNAs (miRs), also play key roles in DKD,… read more here.
Keywords: fibrosis; kidney disease; diabetic kidney; dnm3os ... See more keywords