Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles
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DOI: 10.1007/s00401-019-01981-6
Abstract: Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) were outlined in the current WHO classification of tumors of the nervous system as two distinct histological MB variants. However, they are often considered as cognate… read more here.
Keywords: desmoplastic nodular; dnmb; nodular medulloblastomas; medulloblastomas dnmb ... See more keywords
Molecular progression of SHH-activated medulloblastomas
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DOI: 10.1007/s00401-019-02022-y
Abstract: Medulloblastoma (MB) comprises four main molecular MB subgroups (WNT, SHH, Group 3 and Group 4) with divergent biology, outcomes and subgroup-specific differences in relapses [1–6]. Metastatic recurrences are most common in Group 3 and 4… read more here.
Keywords: progression shh; shh activated; shh; dnmb ... See more keywords