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   Articles with "dnmt" as a keyword



The interaction of RELN–DNMT genes involving in neurotrophin signaling pathway contributes to schizophrenia susceptibility

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recommendations! Published in 2024 at "International Journal of Developmental Neuroscience"

DOI: 10.1002/jdn.10316

Abstract: Schizophrenia belongs to a severe mental illness with complicated clinical presentations, an ill‐defined pathogenesis, and no known cause. Many genetic studies imply that polygenic interaction is important in the development of schizophrenia. The main mechanism… read more here.

Keywords: schizophrenia; dnmt; creb; interaction ... See more keywords

Environmental enrichment improves lifelong persistent behavioral and epigenetic changes induced by early-life stress.

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recommendations! Published in 2021 at "Journal of psychiatric research"

DOI: 10.1016/j.jpsychires.2021.04.008

Abstract: This study aimed to evaluate the effects of environmental enrichment (EE) in Wistar rats subjected to maternal deprivation (MD). MD was performed in the first post-natal days (PND) ten for 3 h/day. The groups were: control;… read more here.

Keywords: hippocampus; dnmt; hdac dnmt; persistent behavioral ... See more keywords

Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling

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recommendations! Published in 2021 at "Communications Biology"

DOI: 10.1038/s42003-021-02291-y

Abstract: Patients with long-standing diabetes have a high risk for cardiac complications that is exacerbated by increased reactive oxygen species (ROS) production. We found that feeding cyanocobalamin (B12), a scavenger of superoxide, not only prevented but… read more here.

Keywords: dnmt socs1; cardiomyopathy type; igf; dnmt ... See more keywords

Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes

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recommendations! Published in 2022 at "SHOCK"

DOI: 10.1097/shk.0000000000001928

Abstract: ABSTRACT Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be responsible for some of these immunosuppressive changes. During sepsis circulating exosomes contain large quantities of DNA methyltransferase (DNMT) mRNAs. We hypothesized that exosomes… read more here.

Keywords: transfer; mrna; dnmt; dnmt mrna ... See more keywords

Abstract 5081: Disruption of DNA methyltransferase (DNMT) 1 confers resistance to DNMT inhibitors in human colorectal cancer cells

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recommendations! Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-5081

Abstract: DNA methyltransferase (DNMT) 1 is responsible for the maintenance and propagation of DNA methylation pattern, and plays an important role in cell survival and proliferation. Thus, targeting DNMT represents a promising approach for cancer treatment.… read more here.

Keywords: aza dcyd; dnmt; aza; dnmt1 ... See more keywords