Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes
Sign Up to like & getrecommendations! Published in 2022 at "SHOCK"
DOI: 10.1097/shk.0000000000001928
Abstract: ABSTRACT Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be responsible for some of these immunosuppressive changes. During sepsis circulating exosomes contain large quantities of DNA methyltransferase (DNMT) mRNAs. We hypothesized that exosomes… read more here.
Keywords: transfer; mrna; dnmt; dnmt mrna ... See more keywords