SPRTN and TDP1/TDP2 Independently Suppress 5-Aza-2'-deoxycytidine-Induced Genomic Instability in Human TK6 Cell Line.
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DOI: 10.1021/acs.chemrestox.2c00213
Abstract: DNA-protein cross-links (DPCs) are generated by internal factors such as cellular aldehydes that are generated during normal metabolism and external factors such as environmental mutagens. A nucleoside analog, 5-aza-2'-deoxycytidine (5-azadC), is randomly incorporated into the… read more here.
Keywords: tdp1 tdp2; tk6; dpcs; dnmt1 dpcs ... See more keywords