DNMT1/miR-130a/ZEB1 Regulatory Pathway Affects the Inflammatory Response in Lipopolysaccharide-Induced Sepsis.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2021.1060
Abstract: Sepsis is a global health care issue that affects millions of people. DNA methyltransferase I (DNMT1)-mediated DNA methylation is involved in a number of human diseases by affecting many types of cellular progression events. However,… read more here.
Keywords: sepsis; aecii cells; dnmt1 mir; 130a zeb1 ... See more keywords
The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells
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DOI: 10.1155/2019/7028901
Abstract: The DNA methyltransferase 1 (DNMT1)/miR-34a axis promoted carcinogenesis of various types of cancers. However, no literature reported its contribution to the stemness of osteosarcoma cancer stem-like cells (OSLCs). We sought to determine whether the DNMT1/miR-34a… read more here.
Keywords: mir 34a; dnmt1 mir; 34a axis; stemness oslcs ... See more keywords
DNMT1/miR-152-3p/SOS1 signaling axis promotes self-renewal and tumor growth of cancer stem-like cells derived from non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Epigenetics"
DOI: 10.1186/s13148-024-01663-5
Abstract: CSLCs(Cancer stem cell-like cells), which are central to tumorigenesis, are intrinsically influenced by epigenetic modifications. This study aimed to elucidate the underlying mechanism involving the DNMT1/miR-152-3p/SOS1 axis in regulating the self-renewal and tumor growth of… read more here.
Keywords: cancer; mir 152; self renewal; dnmt1 mir ... See more keywords