Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia
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DOI: 10.3324/haematol.2021.280329
Abstract: Pre-leukemic clones carrying DNMT3A mutations have a selective advantage and an inherent chemoresistance, however the basis for this phenotype has not been fully elucidated. Mutations affecting the gene TP53 occur in pre-leukemic hema-topoietic stem/progenitor cells… read more here.
Keywords: pseudo mutant; hspc; p53; prel hspc ... See more keywords