Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML.
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DOI: 10.1182/blood.2018862383
Abstract: FLT3, DNMT3A, and NPM1 are the most frequently mutated genes in cytogenetically normal acute myeloid leukemia (AML), but little is known about how these mutations synergize upon co-occurrence. Here we show that triple-mutated AML is… read more here.
Keywords: cell; triple mutated; dnmt3a npm1; mutated aml ... See more keywords