DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia
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DOI: 10.1038/leu.2017.200
Abstract: We investigated the prognostic impact of minimal residual disease (MRD) monitoring in acute myeloid leukemia patients harboring DNA methyltransferase 3A-R882H/-R882C mutations (DNMT3Amut). MRD was determined by real-time quantitative PCR (RQ-PCR) in 1494 samples of 181… read more here.
Keywords: remission; dnmt3amut transcript; transcript levels; transcript ... See more keywords