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DNT1 Downregulation and Increased Ethanol Sensitivity in Transgenic Drosophila Models of Alzheimer's Disease.

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0 Published in 2021 at "Archives of gerontology and geriatrics"

DOI: 10.1016/j.archger.2021.104355

Abstract: Two major pathological hallmarks of Alzheimer's disease (AD) are amyloid plaques and neurofibrillary tangles of hyperphosphorylated tau. Aggregation of amyloid-β (Aβ) is considered as the primary insult in AD. However, failure in treatments based on targetingAβ… read more here.

Keywords: dnt1 downregulation; alzheimer disease; disease; pathological tau ... See more keywords