Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1292
Abstract: Importance Dose-reduced regimens of direct oral anticoagulants (DOACs) may be used for 2 main purposes: dose-adjusted treatment intended as full-intensity anticoagulation (eg, for stroke prevention in atrial fibrillation [AF] in patients requiring dose reduction) or… read more here.
Keywords: dose adjusted; low intensity; treatment; dose reduced ... See more keywords
Comparison of warfarin versus DOACs in patients with concomitant indication for oral anticoagulation undergoing TAVI; results from the ATLAS registry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-019-01968-w
Abstract: The optimal antithrombotic therapy for patients undergoing TAVI with concomitant indication for oral anticoagulation remains unclear. In this high-risk population group, there is a paucity of data with regards to the use of DOACs. In… read more here.
Keywords: anticoagulation; undergoing tavi; concomitant indication; indication oral ... See more keywords
Prescribing trends of oral anticoagulants in England over the last decade: a focus on new and old drugs and adverse events reporting
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-021-02416-4
Abstract: Direct-acting oral anticoagulants (DOACs) are replacing conventional VKA (vitamin K antagonist, i.e., warfarin) for various indications where a therapeutic anticoagulant effect is desired. We evaluated the prescribing patterns of the DOACs and warfarin, cost implications… read more here.
Keywords: oral anticoagulants; year; adverse events; prescribing trends ... See more keywords
Current status of oral anticoagulant adherence in Japanese patients with atrial fibrillation: A claims database analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2021.02.007
Abstract: BACKGROUND Direct oral anticoagulants (DOACs) are widely used for stroke prevention in patients with non-valvular atrial fibrillation (NVAF). We investigated the adherence of DOACs for years known to be associated with the effectiveness in Japanese… read more here.
Keywords: atrial fibrillation; analysis; claims database; doacs ... See more keywords
Morbidity and mortality after fragility hip fracture surgery in patients receiving vitamin K antagonists and direct oral anticoagulants.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2018.04.022
Abstract: INTRODUCTION Early surgical treatment is recommended to reduce morbidity and mortality in patients with fragility hip fractures. Anticoagulation treatment poses a surgical challenge. While the action of vitamin K antagonists (VKAs) can be reversed, for… read more here.
Keywords: fragility hip; doacs; morbidity mortality; mortality ... See more keywords
Thromboprophylaxis for orthopedic surgery; An updated meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis research"
DOI: 10.1016/j.thromres.2020.12.007
Abstract: BACKGROUND Venous thromboembolism (VTE) is a serious complication of orthopedic surgery. Low molecular weight heparin (LMWH) has been the standard of care for thromboprophylaxis in this population. However, direct oral anticoagulants (DOACs) are increasingly being… read more here.
Keywords: orthopedic surgery; vte; surgery; thromboprophylaxis orthopedic ... See more keywords
Dose specific effectiveness and safety of DOACs in patients with non-valvular atrial fibrillation: A Canadian retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2021 at "Thrombosis research"
DOI: 10.1016/j.thromres.2021.05.005
Abstract: BACKGROUND Direct oral anticoagulants (DOACs) have been proven to be effective and safe for prevention of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF). However, suboptimal adherence, variable dosing and use… read more here.
Keywords: low dose; rivaroxaban; cohort; doacs ... See more keywords
Current evidence on the use of direct oral anticoagulants in patients with myeloproliferative neoplasm: a systematic review
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2023.2174515
Abstract: ABSTRACT Introduction Thromboembolic events in myeloproliferative neoplasms (MPNs) are one of the most important causes of mortality and morbidity, in which vitamin K antagonists (VKAs) have been used mostly. Recently, direct oral anticoagulants (DOACs) are… read more here.
Keywords: review; systematic review; direct oral; oral anticoagulants ... See more keywords
Factors influencing oral anticoagulant prescribing decisions for patients with atrial fibrillation: a systematic review of qualitative and quantitative evidence
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DOI: 10.1093/ijpp/riab015.044
Abstract: Despite their efficacy in reducing stroke risk in patients with atrial fibrillation (AF), oral anticoagulants (OACs) remain under-prescribed [1]. Until recently, warfarin has been the dominant OAC. The introduction of direct oral anticoagulants (DOACs) led… read more here.
Keywords: doacs; review; health; choice ... See more keywords
Prevention of venous thromboembolism in patients with cancer with direct oral anticoagulants
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000019000
Abstract: Abstract Background: Patients with cancer are of a high level risk of venous thromboembolism (VTE). Low molecular weight heparin (LMWH) is recommended as the normal treatment for cancer-associated venous thrombosis. Recently, some studies suggest that… read more here.
Keywords: patients cancer; venous thromboembolism; doacs; oral anticoagulants ... See more keywords
Direct oral anticoagulants for venous thromboembolism prophylaxis in orthopaedic trauma: a clear first choice?
Sign Up to like & getrecommendations! Published in 2023 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.18305
Abstract: ‘The brain may devise laws for the blood’ William Shakespeare, Merchant of Venice (1598) Prevention of venous thromboembolism (VTEp) is an integral part in the care of orthopaedic patients. VTE the leading cause of preventable… read more here.
Keywords: vtep; surgery; orthopaedic trauma; risk ... See more keywords