Targeting dormant phenotype acquired mycobacteria using natural products by exploring its important targets: In vitro and in silico studies
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1111997
Abstract: The dormant phenotype of Mycobacterium tuberculosis that develops during infection poses a major challenge in disease treatment, since these bacilli show tolerance to front-line drugs. An in vitro hypoxia dormancy model was established, which produced… read more here.
Keywords: kcal mol; mol; dock score; binding energy ... See more keywords
Teicoplanin is a potential inhibitor of SARS CoV-2 replication enzymes: A docking study
Sign Up to like & getrecommendations! Published in 2020 at "Asian Pacific Journal of Tropical Biomedicine"
DOI: 10.4103/2221-1691.294093
Abstract: Objective: To explore potential inhibitors of viral enzymes of SARS CoV-2. Methods: The in-silico docked potential of anti-viral, antibiotic, and analgesic drugs were studied for inhibition of the nonstructural protein (NSP) 9, NSP3, and NSP15… read more here.
Keywords: inhibitor sars; cov replication; potential inhibitor; teicoplanin potential ... See more keywords