Synthesis, Docking and Anticancer Evaluation of New Pyridine-3-Carbonitrile Derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2020.1870507
Abstract: N'-(2-((4-(Benzo[d][1, 3]dioxol-5-yl)-3-cyano-6-(naphthalen-2-yl)-pyridin-2-yl)oxy)- acetyl)benzohydrazide (6) and hydrazide derivatives (7–10) were synthesized via reaction of 3-cyano-pyridinaceto... read more here.
Keywords: anticancer evaluation; pyridine carbonitrile; docking anticancer; synthesis docking ... See more keywords
Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2023.2175209
Abstract: Abstract New thiazolopyrimidine derivatives 2, 3a-d, 4a-c, 5, 6a-c, and 7a,b were synthesised. All prepared compounds were evaluated by MTT cytotoxicity assay against three human tumour cell lines. Compounds 3c, 3d, 4c, 6a, 6b, and… read more here.
Keywords: design synthesis; synthesis docking; evaluations new; docking anticancer ... See more keywords