Design, synthesis, docking and biological evaluation of chalcones as promising antidiabetic agents.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103527
Abstract: Diabetes mellitus (DM) is a serious chronic metabolic disorder which occurs due to dysfunction of insulin and therapeutic approaches are poor. It is an under estimation that 387 million people currently suffering globally with diabetic… read more here.
Keywords: design synthesis; synthesis docking; biological evaluation; evaluation chalcones ... See more keywords
Synthesis, ADME, Molecular Docking, and Biological Evaluation of New 2-Aminobenzothiazloes
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DOI: 10.2174/1573407219666230512121913
Abstract: In recent years, 2-aminobenzothiazoles were reported as antibacterial, antihelmintic, antitumor, antimalarial, antiviral, analgesic and anti-inflammatory agents. The study aimed to explore new potential 2-aminobenzothiazoles as antibacterial and anthelmintic agents. A favorable two-step method was used… read more here.
Keywords: molecular docking; biological evaluation; synthesis adme; adme molecular ... See more keywords
Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer’s Inhibitors
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DOI: 10.3390/molecules28020559
Abstract: Alzheimer’s disease is a major public brain condition that has resulted in many deaths, as revealed by the World Health Organization (WHO). Conventional Alzheimer’s treatments such as chemotherapy, surgery, and radiotherapy are not very effective… read more here.
Keywords: molecular docking; studies molecular; activity; docking biological ... See more keywords