Molecular docking, QSAR and ADMET based mining of natural compounds against prime targets of HIV
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1420489
Abstract: AIDS is one of the multifaceted diseases and this underlying complexity hampers its complete cure. The toxicity of existing drugs and emergence of multidrug-resistant virus makes the treatment worse. Development of effective, safe and low-cost… read more here.
Keywords: qsar admet; targets hiv; treatment; docking qsar ... See more keywords
Docking and QSAR Studies of Aryl-valproic Acid Derivatives to Identify Antiproliferative Agents Targeting the HDAC8.
Sign Up to like & getrecommendations! Published in 2017 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520616666161019143219
Abstract: BACKGROUND Histone deacetylase 8 (HDAC8) is a plausible target for the development of novel anticancer drugs using a metal-chelating group and hydrophobic moieties as pharmacophores. It is known that valproic acid (administered as its salt,… read more here.
Keywords: hdac8; valproic acid; studies aryl; docking qsar ... See more keywords