A separate assay of released and liposomal encapsulated eribulin in dog plasma by liquid chromatography with tandem mass spectrometry for its application to a pharmacokinetic study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200048
Abstract: Eribulin has been used as a drug for the treatment of metastatic breast cancer and liposomal formulation of eribulin (E7389-LF) is under development to achieve a wider therapeutic index. It is important to separately determine… read more here.
Keywords: dog plasma; plasma liquid; plasma; separate assay ... See more keywords
The Chiral Bioconversion and Pharmacokinetic Analysis of Trelagliptin in Beagle Dog Plasma by LC-MS/MS.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmz105
Abstract: A simple and enantioselective method was developed and validated for the simultaneous determination of (R)- and (S)-trelagliptin in beagle dog plasma by chiral liquid chromatography tandem mass spectrometry. Trelagliptin enantiomers and (R)-rabeprazole (as internal standard,… read more here.
Keywords: trelagliptin beagle; beagle dog; trelagliptin; dog plasma ... See more keywords