Identification of NRAS Downstream Genes with CRISPR Activation Screening
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DOI: 10.3390/biology11111551
Abstract: Simple Summary NRAS mutations constitutively activate cell proliferation signaling in malignant tumors. The elucidation of NRAS downstream signaling genes may lead to the control of NRAS-mutant tumors. Genome-wide CRISPR activation screening was performed on THP-1… read more here.
Keywords: cell; proliferation; crispr activation; dohh hist1h2ac ... See more keywords