Articles with "dolastatin analogues" as a keyword



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Synthesis and biological activity evaluation of dolastatin 10 analogues with N-terminal modifications

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Published in 2017 at "Tetrahedron"

DOI: 10.1016/j.tet.2017.03.006

Abstract: Abstract We have described the synthesis of the two complex units (2 R ,3 R ,4 S )-dolaproine (Dap) and (3 R ,4 S ,5 S )-dolaisoleuine (Dil) of dolastatin 10 from natural amino acids.… read more here.

Keywords: biological activity; dolastatin analogues; activity evaluation; terminal modifications ... See more keywords