Modified substrate specificity of a methyltransferase domain by protein insertion into an adenylation domain of the bassianolide synthetase
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DOI: 10.1186/s13036-019-0195-y
Abstract: BackgroundCreating designer molecules using a combination of select domains from polyketide synthases and/or nonribosomal peptide synthetases (NRPS) continues to be a synthetic goal. However, an incomplete understanding of how protein-protein interactions and dynamics affect each… read more here.
Keywords: adenylation domain; methyltransferase; domain bassianolide; domain ... See more keywords