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   Articles with "domain containing" as a keyword



Adipogenesis associated Mth938 domain containing (AAMDC) protein expression is regulated by alternative polyadenylation and microRNAs

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recommendations! Published in 2019 at "FEBS Letters"

DOI: 10.1002/1873-3468.13449

Abstract: The post‐transcriptional events regulating expression of the adipogenesis associated Mth938 domain containing (AAMDC) protein are poorly understood. Here, we find that AAMDC expresses three isoforms due to alternative polyadenylation (APA) and alternative splicing (AS). Luciferase… read more here.

Keywords: domain containing; mth938 domain; adipogenesis associated; expression ... See more keywords
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Lon domain‐containing protein 1 represses thioredoxin y2 and regulates ROS levels in Arabidopsis chloroplasts

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recommendations! Published in 2019 at "FEBS Letters"

DOI: 10.1002/1873-3468.13664

Abstract: Plant thioredoxins (Trxs) act as antioxidants and function as redox regulators in the chloroplast. Although the regulation of ROS in chloroplasts is well elucidated, the precise regulation mechanism of Trx remains unknown. Here, we characterize… read more here.

Keywords: protein; domain containing; lon domain; lcp1 ... See more keywords

Membrane trafficking functions of the ANTH/ENTH/VHS domain‐containing proteins in plants

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14368

Abstract: Subcellular localization of proteins acting on the endomembrane system is primarily regulated via membrane trafficking. To obtain and maintain the correct protein composition of the plasma membrane and membrane‐bound organelles, the loading of selected cargos… read more here.

Keywords: vhs domain; vhs; anth enth; enth vhs ... See more keywords

LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells.

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recommendations! Published in 2023 at "Molecular oncology"

DOI: 10.1002/1878-0261.13421

Abstract: LIM protein-domain containing protein Ajuba (encoded by AJUBA) functions as a scaffold protein to regulate protein-protein interactions, signaling transduction and genes transcription. AJUBA expression is higher in colorectal cancer (CRC) tissues compared with normal tissues,… read more here.

Keywords: protein ajuba; p53; protein; domain containing ... See more keywords

Nuclear Condensates of WW Domain‐Containing Adaptor With Coiled‐Coil Regulate Mitophagy via Alternative Splicing

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202406759

Abstract: Biomolecular condensates segregate nuclei into discrete regions, facilitating the execution of distinct biological functions. Here, it is identified that the WW domain containing adaptor with coiled‐coil (WAC) is localized to nuclear speckles via its WW… read more here.

Keywords: coil; alternative splicing; coiled coil; domain containing ... See more keywords

A Review of FUN14 Domain‐Containing 1 Involvement in Mitochondrial Biological Processes and Mechanisms Across Various Systems

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recommendations! Published in 2025 at "Cell Biochemistry and Function"

DOI: 10.1002/cbf.70125

Abstract: FUN14 domain‐containing 1 (FUNDC1), an outer mitochondrial membrane protein, has emerged as a critical regulator of mitochondrial quality control and cellular homeostasis. Initially identified as a mitophagy receptor, FUNDC1 orchestrates hypoxia‐induced mitophagy through phosphorylation‐dependent interactions… read more here.

Keywords: involvement mitochondrial; containing involvement; domain containing; fun14 domain ... See more keywords
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Functional analysis of Aarf domain‐containing kinase 1 in Drosophila melanogaster

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recommendations! Published in 2019 at "Developmental Dynamics"

DOI: 10.1002/dvdy.66

Abstract: The ADCK proteins are predicted mitochondrial kinases. Most studies of these proteins have focused on the Abc1/Coq8 subfamily, which contributes to Coenzyme Q biosynthesis. In contrast, little is known about ADCK1 despite its evolutionary conservation… read more here.

Keywords: drosophila; domain containing; aarf domain; containing kinase ... See more keywords
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Overexpression of gene DEP domain containing 1 and its clinical prognostic significance in colorectal cancer

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recommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.23634

Abstract: Colorectal cancer (CRC) is one of the most commonly seen malignancies worldwide, yet its regulatory mechanisms still need to be further illuminated. Abundant evidence revealed that aberrant expression of cancer‐related genes contributes to CRC progression.… read more here.

Keywords: cancer; dep domain; colorectal cancer; domain containing ... See more keywords

Portal hypertension in doublecortin domain-containing protein 2 (DCDC2) related neonatal sclerosing cholangitis.

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recommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"

DOI: 10.1002/jpn3.12414

Abstract: Mutations in doublecortin domain-containing protein 2 (DCDC2) lead to neonatal sclerosing cholangitis (NSC), and portal hypertension (PHTN). The objective of the study was to systematically evaluate PHTN, variceal bleeding, and outcomes of patients with DCDC2-related… read more here.

Keywords: containing protein; neonatal sclerosing; dcdc2 related; doublecortin domain ... See more keywords

The Popeye domain containing gene family encoding a family of cAMP-effector proteins with important functions in striated muscle and beyond

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recommendations! Published in 2019 at "Journal of Muscle Research and Cell Motility"

DOI: 10.1007/s10974-019-09523-z

Abstract: The Popeye domain containing (POPDC) gene family encodes a novel class of membrane-bound cyclic AMP effector proteins. POPDC proteins are abundantly expressed in cardiac and skeletal muscle. Consistent with its predominant expression in striated muscle,… read more here.

Keywords: domain containing; gene family; muscle; popeye domain ... See more keywords

Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4.

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recommendations! Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.07.030

Abstract: Phostensin (PTS) encoded by KIAA1949 is a protein phosphatase 1 (PP1)-binding protein. In order to explore the cellular functions of PTS, we have searched PTS-binding proteins by using co-immunoprecipitation in combination with shotgun proteomics. Here,… read more here.

Keywords: protein; domain containing; protein ehd1; homology domain ... See more keywords