Multivalent targeting and killing of HER2 overexpressing breast carcinoma cells with methotrexate‐encapsulated tetra‐specific non‐overlapping variable domain heavy chain anti‐HER2 antibody‐PEG‐liposomes: In vitro proof‐of‐concept
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DOI: 10.1016/j.ejps.2018.06.019
Abstract: &NA; The variable domain of the heavy chain antibodies (VHHs) is the smallest (15 kDa) intact single domain antigen‐binding fragment. VHHs often exhibit sub‐nanomolar affinity for their designated targets and therefore are receiving increasing attention… read more here.
Keywords: variable domain; domain heavy; her2; domain ... See more keywords