Dynamics and binding interactions of peptide inhibitors of dengue virus entry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Physics"
DOI: 10.1007/s10867-018-9515-6
Abstract: In this study, we investigate the binding interactions of two synthetic antiviral peptides (DET2 and DET4) on type II dengue virus (DENV2) envelope protein domain III. These two antiviral peptides are designed based on the… read more here.
Keywords: dengue virus; dynamics binding; binding site; binding interactions ... See more keywords
Mapping of a unique epitope on domain III of the envelope protein of Tembusu virus.
Sign Up to like & getrecommendations! Published in 2021 at "Virus research"
DOI: 10.1016/j.virusres.2021.198582
Abstract: We recently developed a Tembusu virus (TMUV)-specific monoclonal antibody (MAb) 12F11, which was found to recognize a long amino acid sequence between residues 8 and 77 of domain III of the envelope protein (EDIII). Here,… read more here.
Keywords: iii envelope; envelope; tembusu virus; envelope protein ... See more keywords
A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010573
Abstract: Powassan virus (POWV) is an emerging tick borne flavivirus (TBFV) that causes severe neuroinvasive disease. Currently, there are no approved treatments or vaccines to combat POWV infection. Here, we generated and characterized a nanoparticle immunogen… read more here.
Keywords: domain iii; nanoparticle immunogen; powv; powassan virus ... See more keywords
Domain-Specific Stabilization of Structural and Dynamic Responses of Human Serum Albumin by Sucrose.
Sign Up to like & getrecommendations! Published in 2019 at "Protein and peptide letters"
DOI: 10.2174/0929866526666190122115702
Abstract: BACKGROUND Human Serum Albumin (HSA) is the most abundant protein present in human blood plasma. It is a large multi-domain protein with 585 amino acid residues. Due to its importance in human body, studies on… read more here.
Keywords: state; domain specific; hsa; spectroscopy ... See more keywords
Nanoparticle vaccine based on the envelope protein domain III of Japanese encephalitis virus elicits robust protective immune responses in mice.
Sign Up to like & getrecommendations! Published in 2023 at "Nanomedicine"
DOI: 10.2217/nnm-2022-0298
Abstract: Aim: To develop a vaccine candidate for Japanese encephalitis virus (JEV), for which an effective and safe vaccine is urgently needed. Materials & methods: A vaccine candidate based on domain III of the JEV envelope… read more here.
Keywords: domain iii; immune responses; envelope protein; encephalitis virus ... See more keywords
Use of Envelope Domain III Protein for the Detection of IgG Type Antibodies Specific to Zika Virus by Indirect ELISA
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13030462
Abstract: Zika virus (ZIKV) diagnostics are crucial for proper antenatal and postnatal care and also for surveillance and serosurvey studies. Since the viremia during ZIKV infection is fleeting, serological testing is highly valuable to inform diagnosis.… read more here.
Keywords: domain iii; envelope domain; elisa; virus ... See more keywords
Effects of Adjuvants on the Immunogenicity and Efficacy of a Zika Virus Envelope Domain III Subunit Vaccine
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DOI: 10.3390/vaccines7040161
Abstract: Zika virus (ZIKV), a mosquito-borne flavivirus, has attracted global attention due to its close association with congenital Zika syndrome and neurological diseases, and transmission through additional routes, such as sexual contact. Currently there are no… read more here.
Keywords: vaccine; subunit vaccine; zikv; zika virus ... See more keywords
Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines
Sign Up to like & getrecommendations! Published in 2020 at "Vaccines"
DOI: 10.3390/vaccines8020307
Abstract: The flavivirus envelope protein domain III (EDIII) was an effective immunogen against dengue virus (DENV) and other related flaviviruses. Whether this can be applied to the Zika virus (ZIKV) vaccinology remains an open question. Here,… read more here.
Keywords: protein; envelope; zikv; zika virus ... See more keywords