Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1
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DOI: 10.1128/jvi.02418-16
Abstract: ABSTRACT A dynamic actin cytoskeleton is necessary for viral entry, intracellular migration, and virion release. For HIV-1 infection, during entry, the virus triggers early actin activity by hijacking chemokine coreceptor signaling, which activates a host… read more here.
Keywords: domain kinase; kinase; small molecule; discovery ... See more keywords