An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7
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DOI: 10.1007/s10875-021-01161-w
Abstract: The NLRP3 inflammasome is a vital mediator of innate immune responses. There are numerous NLRP3 mutations that cause NLRP3-associated autoinflammatory diseases (NLRP3-AIDs), mostly in or around the NACHT domain. Here, we present a patient with… read more here.
Keywords: autoinflammatory; lrr domain; mutation; domain nlrp3 ... See more keywords