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   Articles with "domain proteins" as a keyword



Role of Bin‐Amphiphysin‐Rvs (BAR) domain proteins in mediating neuronal signaling and disease

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recommendations! Published in 2022 at "Synapse"

DOI: 10.1002/syn.22248

Abstract: Several proteins contain signaling domains that can regulate the cell membrane dynamics as well as the underlying cytoskeleton. Among these, Bin‐Amphiphysin‐Rvs (BAR) domain‐containing proteins, with their membrane deforming properties, have emerged as the key players… read more here.

Keywords: bin amphiphysin; bar domain; bar; amphiphysin rvs ... See more keywords
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J-Domain Proteins in Bacteria and their Viruses.

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recommendations! Published in 2020 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2020.04.014

Abstract: Molecular chaperones maintain cellular protein homeostasis by acting at almost every step in protein biogenesis pathways. The DnaK/HSP70 chaperone has been associated with almost every known essential chaperone functions in bacteria. To act as a… read more here.

Keywords: proteins bacteria; dnak; domain proteins; bacteria viruses ... See more keywords

HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.

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recommendations! Published in 2019 at "Molecular cell"

DOI: 10.1016/j.molcel.2019.12.009

Abstract: Bacteria are continually challenged by foreign invaders, including bacteriophages, and have evolved a variety of defenses against these invaders. Here, we describe the structural and biochemical mechanisms of a bacteriophage immunity pathway found in a… read more here.

Keywords: bacteriophage; atpase; domain proteins; horma domain ... See more keywords

Tandem GGDEF-EAL Domain Proteins Pleiotropically Modulate c-di-GMP Metabolism Enrolled in Bacterial Cellulose Biosynthesis.

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recommendations! Published in 2025 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.4c07301

Abstract: Cyclic diguanosine monophosphate (c-di-GMP) is a crucial secondary messenger that regulates bacterial cellulose (BC) synthesis. It is synthesized by diguanylate cyclase (DGC) containing a Gly-Gly-Asp/Glu-Glu-Phe (GGDEF) domain and degraded by phosphodiesterase (PDE) with a Glu-Ala-Leu… read more here.

Keywords: domain proteins; bacterial cellulose; ggdef eal; eal ... See more keywords
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Coarse-Grained Modeling of Multiple Pathways in Conformational Transitions of Multi-Domain Proteins

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recommendations! Published in 2021 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.1c00286

Abstract: Large-scale conformational transitions in multi-domain proteins are often essential for their functions. To investigate the transitions, it is necessary to explore multiple potential pathways, which involve different intermediate structures. Here, we present a multi-basin (MB)… read more here.

Keywords: domain proteins; transitions multi; coarse grained; multi domain ... See more keywords

Identification of subfunctionalized aggregate-remodeling J-domain proteins in Arabidopsis thaliana.

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recommendations! Published in 2022 at "Journal of experimental botany"

DOI: 10.1093/jxb/erac514

Abstract: J-domain proteins (JDPs) are critical components of the cellular protein quality control machinery, playing crucial roles in preventing the formation and solubilizing cytotoxic protein aggregates. Bacteria, yeast and plants additionally have large, multimeric Hsp100-class disaggregases… read more here.

Keywords: aggregate remodeling; arabidopsis thaliana; protein aggregates; domain proteins ... See more keywords

SlVQ15 Interacts with Jasmonate-ZIM Domain Proteins and SlWRKY31 to Regulate Defense Response in Tomato.

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recommendations! Published in 2022 at "Plant physiology"

DOI: 10.1093/plphys/kiac275

Abstract: Botrytis cinerea is one of the most widely distributed and harmful pathogens worldwide. Both the phytohormone jasmonate (JA) and the VQ motif-containing proteins play crucial roles in plant resistance to B. cinerea. However, their crosstalk… read more here.

Keywords: cinerea; slvq15; zim domain; resistance cinerea ... See more keywords

Distinct strategies of diguanylate cyclase domain proteins on inhibition of virulence and interbacterial competition by agrobacteria

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recommendations! Published in 2025 at "mBio"

DOI: 10.1128/mbio.00039-25

Abstract: ABSTRACT Diguanylate cyclases (DGCs) synthesize bis-(3′,5′)-cyclic diguanylic acid (c-di-GMP), a critical bacterial second messenger that coordinates diverse biological processes. Agrobacterium tumefaciens, a plant pathogen causing crown gall disease, relies on type IV secretion system for… read more here.

Keywords: domain proteins; interbacterial competition; gmp; virulence ... See more keywords

Differential incorporation of SUN-domain proteins into LINC complexes is coupled to gene expression

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recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0197621

Abstract: LInkers of Nucleoskeleton and Cytoskeleton (LINC) complexes, composed of SUN and KASH-domain proteins, span the nuclear envelope and physically connect the nuclear interior to cytoskeletal elements. Most human cells contain two SUN proteins, Sun1 and… read more here.

Keywords: linc complexes; domain proteins; linc; gene expression ... See more keywords

Widespread evolutionary crosstalk among protein domains in the context of multi-domain proteins

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recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0203085

Abstract: Domains are distinct units within proteins that typically can fold independently into recognizable three-dimensional structures to facilitate their functions. The structural and functional independence of protein domains is reflected by their apparent modularity in the… read more here.

Keywords: context multi; domain proteins; protein domains; multi domain ... See more keywords

A redox-active crosslinker reveals an essential and inhibitable oxidative folding network in the endoplasmic reticulum of malaria parasites

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recommendations! Published in 2021 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1009293

Abstract: Malaria remains a major global health problem, creating a constant need for research to identify druggable weaknesses in P. falciparum biology. As important components of cellular redox biology, members of the Thioredoxin (Trx) superfamily of… read more here.

Keywords: malaria; domain proteins; endoplasmic reticulum; biology ... See more keywords