Development of Inhibitors Targeting the V-Domain Ig Suppressor of T Cell Activation Signal Pathway.
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DOI: 10.1021/acs.jmedchem.2c00803
Abstract: Blockade of cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) has produced considerable therapeutic effect, but only in a fraction of patients, so more targets are being investigated. VISTA… read more here.
Keywords: domain suppressor; suppressor cell; cell; cell activation ... See more keywords