Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it
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DOI: 10.1093/nar/gkx812
Abstract: Abstract Telomeric repeat binding factor 2 (TRF2) folds human telomeres into loops to prevent unwanted DNA repair and chromosome end-joining. The N-terminal basic domain of TRF2 (B-domain) protects the telomeric displacement loop (D-loop) from cleavage… read more here.
Keywords: basic domain; dna; domain trf2; loop ... See more keywords